Amoxicillin: An Effective Antibacterial Medicine

About Amoxicillin: Amoxicillin is an antibiotic belonging to the class of penicillins which are ?-lactams. It has broad spectrum activity against many Gram-positive and some Gram-negative bacteria. Amoxicillin is a bactericidal, semi-synthetic antibiotic. It is used in the treatment of several bacterial infections. Amoxicillin can be administered via oral route or as an injectable solution in case of severe cases. Amoxicillin is not resistant to penicillinase or other ?-lactamase enzymes.

How Amoxicillin Works: Amoxicillin interferes with the synthesis of the bacterial cell walls which are composed of peptidoglycans. Amoxicillin inhibits transpeptidase enzymes, which are responsible for the cross-linking of the cell wall components. Cell walls are essential for bacterial survival. They act as a barrier to prevent substances from entering in and leaking out of the cell. Cell wall deficient forms of the organisms are formed when they multiply in the presence of Amoxicillin, and the intracellular contents leak out. This leads to cell death, hence Amoxicillin is bactericidal in action and most lethal in the phase in which bacteria are rapidly multiplying. Peptidoglycan cell wall is not synthesised by higher animals. Hence, Amoxicillin is not toxic to humans. In Gram-positive organisms, the cell wall is almost entirely composed of peptidoglycan and is much thicker than in Gram-negative bacteria. Hence, Amoxicillin is more effective against Gram-positive organisms. The presence of tissue fluids, pus and blood do not interfere with its antibacterial action.

How To Take Amoxicillin: Buy Amoxicillin No Prescription is active against Gram-positive bacteria like staphylococci, streptococci, pneumococci, meningococci, gonococci, anthrax bacilli, listeria, clostridia, corynebacteria and Gram -negative bacteria like E.coli, H.influenzae, Salmonella and Shigella species. Buy Amoxicillin Without Prescription can be used for the treatment of urinary and respiratory tract infections like sinusitis, bronchitis, pneumonia, otitis media, meningitis, sub-acute bacterial endocarditis, septicaemia and anti-H.pylori regimens. Amoxicillin No Prescription is available as oral capsules or tablets of 250 mg and 500 mg strengths. It is also available as powder for oral suspension with each 5 ml containing 125 mg, 200 mg, 250 mg or 400 mg of Amoxicillin Canada. For adults and children older than ten years (body weight more than 40 kg), the oral dose is 250 mg - 500 mg taken thrice daily, preferably after meals. Higher doses of up to 1000 mg three times a day may be required for more severe infections. For younger children the dose is 125 mg -250 mg three times a day.
For parenteral use Buy Amoxicillin is available as 250 mg and 500 mg vials for intramuscular or intravenous use. In adults the dose is 500 mg to 1 g two times a day if renal function is normal. In children the dose is 50 mg/kg/day i.m. or 100-200 mg/kg/day i.v. in two divided doses. The dose and interval has to be adjusted in cases of impaired renal function. Amoxicillin Without Prescription is also available in combination with clavulanic acid (a ?-lactamase inhibitor) to overcome resistant organisms.

Precautions And Side Effects Of Amoxicillin: Amoxicillin No Prescription should be used with caution in patients having deranged renal function, history of allergies, suspected glandular fever, cytomegalovirus infection in leukemias, as it causes a rash in these conditions. Buy Amoxicillin Canada should not to be used in case of allergy to penicillins of cephalosporins. Amoxicillin Without Prescription reduces effectiveness of oral contraceptives. Diuretics, phenylbutazone, allopurinol, probenicid NSAIDs decrease the renal elimination of amoxicillin, increasing its plasma concentration.The common side effects of Amoxicillin are nausea, diarrhoea and rash. Less common ones include vomiting, hives, itching. The rare side effects of Buy Amoxicillin are dizziness, convulsions, severe allergic reactions, colitis, jaundice or hepatitis.

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